Research Associate

I am a biophysicist working on super-resolution fluorescence microscopy in the Lee Lab. My current work focuses on estimating the orientation of single molecules using optical microscopes.

Before I joined the Lee Lab in October 2019, I studied bioengineering at the University of Antwerp (Belgium) and biophysics at KU Leuven (Belgium) during which I worked on the development of a novel method for spectral single-molecule localization microscopy in the group of Prof. Peter Dedecker.

Publications

POLCAM: instant molecular orientation microscopy for the life sciences.
E Bruggeman, O Zhang, L-M Needham, M Körbel, S Daly, M Cheetham, R Peters, T Wu, AS Klymchenko, SJ Davis, EK Paluch, D Klenerman, MD Lew, K O'Holleran, SF Lee
Nature methods
(2024)
21
dSTORM of actin in fixed HeLa cells v1
E Bruggeman, R peters
(2024)
Live-cell imaging of the plasma membrane of Jurkat T cells v1
E Bruggeman, M Körbel
(2024)
Preparation and imaging of lipid bilayer-coated silica microspheres v1
E Bruggeman
(2024)
Single-molecule orientation estimation using a polarisation camera
E Bruggeman
(2024)
High-density volumetric super-resolution microscopy
S Daly, J Ferreira Fernandes, E Bruggeman, A Handa, R Peters, S Benaissa, B Zhang, JS Beckwith, EW Sanders, RR Sims, D Klenerman, SJ Davis, K O'Holleran, SF Lee
Nature Communications
(2024)
15
High-density volumetric super-resolution microscopy
S Daly, J Ferreira Fernandes, E Bruggeman, A Handa, R Peters, S Benaissa, B Zhang, JS Beckwith, EW Sanders, RR Sims, D Klenerman, SJ Davis, K O’Holleran, SF Lee
Nature Communications
(2024)
15
TAB-PAINT imaging of alpha-synuclein fibrils using Nile Red v1
E Bruggeman
(2024)
Imaging single SYTOX Orange molecules on a PLL-coated cover glass v1
E Bruggeman
(2024)
Imaging single AF647 molecules immobilised in PVA on a cover glass v1
E Bruggeman
(2024)

Postgraduate student