Dr Lisa-Maria Needham

Project: Developing new fluorophores for super-resolution and single-molecule fluorescence Imaging.

Publications

ThX-a next-generation probe for the early detection of amyloid aggregates

L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee

Chemical science

(2020)

4578

(doi: 10.1039/c9sc04730a)

Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

S Basu, O Shukron, D Hall, P Parutto, A Ponjavic, D Shah, W Boucher, D Lando, W Zhang, N Reynolds, LH Sober, A Jartseva, R Ragheb, X Ma, J Cramard, R Floyd, G Brown, J Balmer, TA Drury, AR Carr, L-M Needham, A Aubert, G Communie, K Gor, M Steindel, L Morey, E Blanco, T Bartke, L Di Croce, I Berger, C Schaffitzel, SF Lee, TJ Stevens, D Klenerman, BD Hendrich, D Holcman, ED Laue

BioRxiv

(2020)

2020.04.03.003178

(doi: 10.1101/2020.04.03.003178)

vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy

A Spark, A Kitching, D Esteban-Ferrer, A Handa, A Carr, L-M Needham, A Ponjavic, MDC Santos, J McColl, C Leterrier, S Davis, R Henriques, S Lee

(2020)

2020.01.20.912733

(doi: 10.1101/2020.01.20.912733)

ThX: a next generation probe for the early detection of amyloid aggregates

L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee

BIOPHYSICAL JOURNAL

(2019)

121

(doi: 10.1101/713594)

Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization

K Mueller

Cell Rep

(2019)

3124

(doi: 10.1016/j.celrep.2019.05.038)

Spectrally Resolved Photodynamics of Individual Emitters in Large-Area Monolayers of Hexagonal Boron Nitride.

HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee

ACS nano

(2019)

4538

(doi: 10.1021/acsnano.9b00274)

Spectrally-Resolved Photodynamics of Individual Emitters in Large-Area Monolayers of Hexagonal-Boron Nitride

HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee

(2019)

(doi: 10.48550/arxiv.1901.02793)

FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells

S Basu, L-M Needham, D Lando, EJR Taylor, KJ Wohlfahrt, D Shah, W Boucher, YL Tan, LE Bates, O Tkachenko, J Cramard, BC Lagerholm, C Eggeling, B Hendrich, D Klenerman, SF Lee, ED Laue

Nat Commun

(2018)

2520

(doi: 10.1038/s41467-018-04486-0)