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  • Currently displaying 121 - 140 of 273 publications
Author(s)
Publication title
Journal Name
Publication year
Spectrally-Resolved Photodynamics of Individual Emitters in Large-Area Monolayers of Hexagonal-Boron Nitride
HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee
(2019)
(doi: 10.48550/arxiv.1901.02793)
Mapping Surface Hydrophobicity of α‑Synuclein Oligomers at the Nanoscale
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
Nano Lett
(2018)
18
(doi: 10.1021/acs.nanolett.8b02916)
Redistribution of proteasomes through diffusion and cytoskeleton-dependent mechanisms upon stress induced by protein aggregates
MJ Morten, Y Zhang, B Li, JX Meng, K Jiang, L Sirvio, JE Lee, AH Lippert, M Burridge, KDP Prieto, AR Carr, A Ponjavic, SF Lee, D Finley, D Klenerman, Y Ye
(2018)
(doi: 10.1101/487702)
Machine Learning for Analysis of Time-Resolved Luminescence Data
N Đorđević, JS Beckwith, M Yarema, O Yarema, A Rosspeintner, N Yazdani, J Leuthold, E Vauthey, V Wood
ACS Photonics
(2018)
5
(doi: 10.1021/acsphotonics.8b01047)
Mechanisms of integrin αVβ5 clustering in flat clathrin lattices
A Zuidema, W Wang, M Kreft, L Te Molder, L Hoekman, OB Bleijerveld, L Nahidiazar, H Janssen, A Sonnenberg
J Cell Sci
(2018)
131
(doi: 10.1242/jcs.221317)
Sensitive light-sheet microscopy in multiwell plates using an AFM cantilever.
A Ponjavic, Y Ye, E Laue, SF Lee, D Klenerman
Biomedical Optics Express
(2018)
9
(doi: 10.1364/BOE.9.005863)
Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA-mDia2 signaling and filopodium formation
E Argenzio, J Klarenbeek, KM Kedziora, L Nahidiazar, T Isogai, A Perrakis, K Jalink, WH Moolenaar, M Innocenti
Journal of Biological Chemistry
(2018)
293
(doi: 10.1074/jbc.ra118.002779)
Nanoscopic characterization of individual endogenous protein aggregates in human neuronal cells
DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M-G Spillantini, D Klenerman, MH Horrocks
ChemBioChem
(2018)
19
(doi: 10.1002/cbic.201800209)
Cover Feature: Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells (ChemBioChem 19/2018)
DR Whiten, Y Zuo, L Calo, M Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M Spillantini, D Klenerman, MH Horrocks
ChemBioChem
(2018)
19
(doi: 10.1002/cbic.201800547)
Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution.
D Klenerman
Analytical Chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b02226)
Analysis of nanobody paratopes reveals greater diversity than classical antibodies
LS Mitchell, LJ Colwell
Protein Eng Des Sel
(2018)
31
(doi: 10.1093/protein/gzy017)
Fabrication of Scaffold-Based 3D Magnetic Nanowires for Domain Wall Applications
D Sanz-Hernández, RF Hamans, J Osterrieth, J-W Liao, L Skoric, JD Fowlkes, PD Rack, A Lippert, SF Lee, R Lavrijsen, A Fernández-Pacheco
Nanomaterials (Basel, Switzerland)
(2018)
8
(doi: 10.3390/nano8070483)
FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells
S Basu, L-M Needham, D Lando, EJR Taylor, KJ Wohlfahrt, D Shah, W Boucher, YL Tan, LE Bates, O Tkachenko, J Cramard, BC Lagerholm, C Eggeling, B Hendrich, D Klenerman, SF Lee, ED Laue
Nature communications
(2018)
9
(doi: 10.1038/s41467-018-04486-0)
Single molecule characterisation of the interactions between extracellular chaperones and toxic α-synuclein oligomers
DR Whiten, D Cox, MH Horrocks, CG Taylor, S De, P Flagmeier, L Tosatto, JR Kumita, H Ecroyd, CM Dobson, D Klenerman, MR Wilson
Cell Rep
(2018)
23
(doi: 10.1016/j.celrep.2018.05.074)
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease
MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, AY Baev, AV Berezhnov, Z Yao, D Little, B Banushi, AS Al-Menhali, RT Ranasinghe, DR Whiten, R Yapom, KS Dolt, MJ Devine, P Gissen, T Kunath, M Jaganjac, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
Nature communications
(2018)
9
(doi: 10.1038/s41467-018-04422-2)
A sticky situation: Aberrant protein–protein interactions in Parkinson’s disease
J Brown, MH Horrocks
Semin Cell Dev Biol
(2018)
99
(doi: 10.1016/j.semcdb.2018.05.006)
Single-Molecule Light-Sheet Imaging of Suspended T Cells.
A Ponjavic, J McColl, AR Carr, AM Santos, K Kulenkampff, A Lippert, SJ Davis, D Klenerman, SF Lee
Biophys J
(2018)
114
(doi: 10.1016/j.bpj.2018.02.044)
Weighing one protein with light.
SF Lee, D Klenerman
Science
(2018)
360
(doi: 10.1126/science.aat5851)
Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell
D Lando, S Basu, TJ Stevens, A Riddell, KJ Wohlfahrt, Y Cao, W Boucher, M Leeb, LP Atkinson, SF Lee, B Hendrich, D Klenerman, ED Laue
Nature protocols
(2018)
13
(doi: 10.1038/nprot.2018.017)
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
S Qamar, G Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, EC Phillips, A Miyashita, D Williams, F Ströhl, W Meadows, R Ferry, VJ Dardov, GG Tartaglia, LA Farrer, GS Kaminski Schierle, CF Kaminski, CE Holt, PE Fraser, G Schmitt-Ulms, D Klenerman, T Knowles, M Vendruscolo, P St George-Hyslop
Cell
(2018)
173
(doi: 10.1016/j.cell.2018.03.056)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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