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  • Currently displaying 1 - 20 of 252 publications
Author(s)
Publication title
Journal Name
Publication year
Patch deconvolution for Fourier light-field microscopy.
B Fu, CL Jones, D Heraghty, S Yang, C O'Brien-Ball, V Junghans, H Yang, D Klenerman, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee
Biophysical journal
(2026)
(doi: 10.1016/j.bpj.2026.01.034)
Volumetric Single‐Molecule Tracking Inside Subcellular Structures
S Daly, JE Chambers, C Jones, B Fu, JD Manton, JS Beckwith, SJ Marciniak, DC Gershlick, SF Lee
Small (Weinheim an der Bergstrasse, Germany)
(2026)
(doi: 10.1002/smll.202509162)
Protein-protein interactions drive differences in the spatiotemporal dynamics of transcription factors NANOG and SOX2 in naïve pluripotent cells
GG Agsu, Y Cao, D Jain, SE Strawbridge, S Daly, Z Zhang, A Wurmser, K Bowers, IO De Almeida, G Nikolenyi, S Berger, M Jonaitis, K Guma’a, T Pauzaite, S Maretvadakethope, L Bates, JA Nathan, BD Hendrich, R Perez-Carrasco, KJ Chalut, D Klenerman, TE Boroviak, SF Lee, D Holcman, S Basu
(2025)
(doi: 10.64898/2025.12.03.691924)
SMOLM-LFM: ratiometric single molecule orientation without polarizers
AG Vesga, L Aleman-Castaneda, HS Heil, S Daly, E Bruggeman, SF Lee, S Brasselet, R Henriques
(2025)
(doi: 10.1101/2025.11.26.690201)
Stress-Induced Reorganization of Proteasomes Through Diffusion and Cytoskeleton-Dependent Mechanisms.
MJ Morten, Y Zhang, B Li, JX Meng, K Jiang, L Sirvio, J-E Lee, AH Lippert, M Burridge, KD Pulgar Prieto, AR Carr, A Ponjavic, SF Lee, D Finley, D Klenerman, Y Ye
Small (Weinheim an der Bergstrasse, Germany)
(2025)
22
(doi: 10.1002/smll.202506260)
Neurodegeneration emerges at a cellular tipping point between aggregate accumulation and removal.
MW Cotton, S Venkatesan, JS Beckwith, D Böken, CK Xu, E Fertan, JC Breiter, LE Berkowicz, LS Salazar, A Von Schulze, EA Andrzejewska, EE Brock, HL Han, MM Schneider, DD Sahtoe, D Baker, JB Rowe, A Goriely, WA McEwan, TPJ Knowles, SF Lee, R Halfmann, D Klenerman, G Meisl
(2025)
(doi: 10.1101/2025.09.08.674880)
α-Synuclein driven cell susceptibility in Parkinson’s disease
S Lee, J Breiter, J Beckwith, E Brock, J Lachica, C Toomey, B Fu, M Ryten, L Weiss, N Wood, S Gandhi, M Vendruscolo
(2025)
(doi: 10.21203/rs.3.rs-7375981/v1)
Large-scale visualization of α-synuclein oligomers in Parkinson's disease brain tissue.
R Andrews, B Fu, CE Toomey, JC Breiter, J Lachica, JS Beckwith, R Tian, EE Brock, L-M Needham, GJ Chant, C Loiseau, A Deconfin, K Baspin, R Popovic, J Evans, Y Goh, B Kurt, L Senicar, M Edmonds, T Bartels, N Bengoa-Vergniory, PJ Magill, Z Jaunmuktane, OJ Freeman, BJM Taylor, J Hardy, T Lashley, M Ryten, M Vendruscolo, NW Wood, LE Weiss, S Gandhi, SF Lee
Nature biomedical engineering
(2025)
(doi: 10.1038/s41551-025-01496-4)
Nano-org, a functional resource for single-molecule localisation microscopy data
S Shirgill, DJ Nieves, JA Pike, MA Ahmed, H Abbott, MHH Baragilly, K Savoye, JD Worboys, KS Hazime, E Bruggeman, A Garcia, DJ Williamson, P Rubin-Delanchy, R Peters, DM Davis, R Henriques, SF Lee, DM Owen
Nature Communications
(2025)
16
(doi: 10.1038/s41467-025-63674-x)
Species-specific surface dwell times and accumulation of microbes investigated by holographic microscopy.
EE Brock, SA Matthews, EJ Cohen, S Nakamura, LG Wilson
Philos Trans A Math Phys Eng Sci
(2025)
383
(doi: 10.1098/rsta.2024.0265)
T-cell signaling relies on partial CD45-exclusion at sub-micron sized cellular contacts
M Kotowski, DF Heraghty, M Körbel, D Banik, Z Zhang, S Kedia, B Fu, J McColl, B Li, J Clarke, M Fellermeyer, Y Lui, G Bossi, DK Cole, H Chen, E Basiarz, S Sharma, E Petsalaki, CJ Tape, B de Wet, SF Lee, AM Santos, D Klenerman, SJ Davis
(2025)
(doi: 10.1101/2025.08.29.673015)
Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson’s disease
JR Evans, M Grant-Peters, JS Beckwith, CE Toomey, R Popovic, JC Breiter, JW Brenton, A Fairbrother-Browne, S Strohbuecker, J Lachica, M Rodriguez-Lopez, EE Brock, B Fu, L Nahidiazar, P Lopez-Garcia, R Ferguson, RS Saleeb, H Lucas-Clarke, A Penverne, K D’Sa, CW Pang, MH Horrocks, M Vendruscolo, N Wood, SF Lee, M Ryten, S Gandhi
(2025)
(doi: 10.1101/2025.08.25.671921)
α-Synuclein driven cell susceptibility in Parkinson’s disease
JC Breiter, JS Beckwith, EE Brock, J Lachica, CE Toomey, B Fu, M Ryten, LE Weiss, NW Wood, S Gandhi, M Vendruscolo, SF Lee
(2025)
(doi: 10.1101/2025.08.19.670819)
DHPSFU: a Fiji plugin for fast and accurate double helix-PSF 3D single-molecule localisation microscopy.
Z Zhang, A Ochirova, S Liu, AD Herbert, Y Wu, W Boucher, SF Lee, ED Laue, D Klenerman, A Ponjavic
Scientific Reports
(2025)
15
(doi: 10.1038/s41598-025-15623-3)
Patch deconvolution for Fourier light-field microscopy
B Fu, CL Jones, D Heraghty, S Yang, C O’Brien-Ball, V Junghans, H Yang, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee
(2025)
(doi: 10.1101/2025.06.13.659385)
Volumetric single-molecule tracking inside subcellular structures
S Daly, JE Chambers, C Jones, B Fu, JD Manton, JS Beckwith, SJ Marciniak, DC Gershlick, SF Lee
(2025)
(doi: 10.1101/2025.06.09.658280)
Advanced image processing methods for 3D high-throughput microscopy
B Fu
(2025)
(doi: 10.17863/CAM.118852)
The Origin of Single-Molecule Sensitivity in Label-Free Solution-Phase Optical Microcavity Detection.
CA Saavedra Salazar, D Sole-Barber, S Wan, JK Rasch, M Reitz, B Cullinane, N Asgari, L-M Needham, J Yuen-Zhou, RH Goldsmith
ACS nano
(2025)
19
(doi: 10.1021/acsnano.4c16276)
3D Super-Resolution Imaging of PSD95 Reveals an Abundance of Diffuse Protein Supercomplexes in the Mouse Brain.
S Daly, E Bulovaite, A Handa, K Morris, L Muresan, C Adams, T Kaizuka, A Kitching, A Spark, G Chant, K O Holleran, SGN Grant, MH Horrocks, SF Lee
ACS Chem Neurosci
(2024)
16
(doi: 10.1021/acschemneuro.4c00684)
Vortex Light Field Microscopy: 3D spectral single-molecule imaging with a twist
B Zhang, S Daly, C Zhu, MO Lenz, LE Weiss, L-M Needham, R Peters, SF Lee, K O’Holleran
Optica
(2024)
11
(doi: 10.1364/OPTICA.534148)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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