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  • Currently displaying 61 - 80 of 232 publications
Author(s)
Publication title
Journal Name
Publication year
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation.
A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, M Puigdellívol, A Bruzas, MA Burguillos, RB Dodd, F Chen, Y Zhang, P Flagmeier, L-M Needham, M Enomoto, S Qamar, J Henderson, J Walter, PE Fraser, D Klenerman, SF Lee, P St George-Hyslop, GC Brown
The Journal of biological chemistry
(2021)
296
(doi: 10.1016/j.jbc.2021.100631)
Two RuII Linkage Isomers with Distinctly Different Charge Transfer Photophysics
J Tisaun, B Laramée-Milette, JS Beckwith, J Bierwagen, GS Hanan, C Reber, A Hauser, C Moucheron
Inorganic Chemistry
(2021)
60
(doi: 10.1021/acs.inorgchem.0c03371)
Multicolor Localization-Based Super Resolution Microscopy.
L Nahidiazar, R Harkes
(2021)
2350
(doi: 10.1007/978-1-0716-1593-5_5)
Single-molecule fluorescence detection of a tricyclic nucleoside analogue
GN Samaan, MK Wyllie, JM Cizmic, L-M Needham, D Nobis, K Ngo, S Andersen, SW Magennis, SF Lee, BW Purse
Chemical science
(2020)
12
(doi: 10.1039/d0sc03903a)
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, while the Alzheimer’s R47H mutant does the opposite
A Vilalta, Y Zhou, J Sevalle, J Griffin, K Satoh, D Allendorf, S De, M Puigdellívol, A Bruzas, M Burguillos, R Dodd, F Chen, Y Zhang, P Flagmeier, L-M Needham, M Enomoto, S Qamar, J Henderson, J Walter, P Fraser, D Klenerman, S Lee, P St George-Hyslop, G Brown
(2020)
(doi: 10.1101/2020.12.03.409995)
Amyloid precipitation in biofluids using a structure-specific chemical antibody
M Rodrigues, P Bhattacharjee, A Brinkmalm, D Do, C Pearson, S De, A Ponjavic, J Varela, F Ruggeri, I Baudrexel, J Lee, A Carr, K Kulenkampff, T Knowles, H Zetterberg, T Snaddon, S Gandhi, S Lee, D Klenerman
(2020)
(doi: 10.21203/rs.3.rs-81521/v1)
vLUME: 3D virtual reality for single-molecule localization microscopy
S Lee, A Handa, L-M Needham, A Carr, A Ponjavic, J McColl
Nat Methods
(2020)
17
(doi: 10.1038/s41592-020-0962-1)
A Comparative Photophysical Study of Structural Modifications of Thioflavin T‑Inspired Fluorophores
L-M Needham, J Weber, CM Pearson, DT Do, F Gorka, G Lyu, SE Bohndiek, TN Snaddon, SF Lee
J Phys Chem Lett
(2020)
11
(doi: 10.1021/acs.jpclett.0c01549)
Single molecule light field microscopy
RR Sims, SA Rehman, MO Lenz, SI Benaissa, E Bruggeman, A Clark, EW Sanders, A Ponjavic, L Muresan, SF Lee, K O’Holleran
Optica
(2020)
7
(doi: 10.1364/optica.397172)
Single-molecule visualization of DNA G-quadruplex formation in live cells.
M Di Antonio, A Ponjavic, A Radzevičius, RT Ranasinghe, M Catalano, X Zhang, J Shen, L-M Needham, SF Lee, D Klenerman, S Balasubramanian
Nature chemistry
(2020)
12
(doi: 10.1038/s41557-020-0506-4)
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
FA Aprile, P Sormanni, M Podpolny, S Chhangur, L-M Needham, FS Ruggeri, M Perni, R Limbocker, GT Heller, T Sneideris, T Scheidt, B Mannini, J Habchi, SF Lee, PC Salinas, TPJ Knowles, CM Dobson, M Vendruscolo
Proceedings of the National Academy of Sciences
(2020)
117
(doi: 10.1073/pnas.1919464117)
Data analysis in transient electronic spectroscopy–an experimentalist's view
JS Beckwith, CA Rumble, E Vauthey
International Reviews in Physical Chemistry
(2020)
39
(doi: 10.1080/0144235x.2020.1757942)
Distinct domain requirements for EAP45 in HIV budding, late endosomal recruitment, and cytokinesis
B Meng, P Vallejo Ramirez, K Scherer, E Bruggeman, J Kenyon, C Kaminski, A Lever
bioRxiv
(2020)
(doi: 10.1101/2020.05.23.112607)
Single Molecule Light Field Microscopy
R Sims, S Abdul Rehman, M Lenz, A Clark, E Sanders, A Ponjavic, L Muresan, S Lee, K O’Holleran
(2020)
(doi: 10.1101/2020.05.20.104802)
ThX-a next-generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee
Chemical science
(2020)
11
(doi: 10.1039/c9sc04730a)
Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics
S Basu, O Shukron, D Hall, P Parutto, A Ponjavic, D Shah, W Boucher, D Lando, W Zhang, N Reynolds, LH Sober, A Jartseva, R Ragheb, X Ma, J Cramard, R Floyd, G Brown, J Balmer, TA Drury, AR Carr, L-M Needham, A Aubert, G Communie, K Gor, M Steindel, L Morey, E Blanco, T Bartke, L Di Croce, I Berger, C Schaffitzel, SF Lee, TJ Stevens, D Klenerman, BD Hendrich, D Holcman, ED Laue
BioRxiv
(2020)
(doi: 10.1101/2020.04.03.003178)
The Costs of Close Contacts: Visualizing the Energy Landscape of Cell Contacts at the Nanoscale.
K Kulenkampff, AH Lippert, J McColl, AM Santos, A Ponjavic, E Jenkins, J Humphrey, A Winkel, K Franze, SF Lee, SJ Davis, D Klenerman
Biophysical journal
(2020)
118
(doi: 10.1016/j.bpj.2020.01.019)
vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy
A Spark, A Kitching, D Esteban-Ferrer, A Handa, A Carr, L-M Needham, A Ponjavic, MDC Santos, J McColl, C Leterrier, S Davis, R Henriques, S Lee
(2020)
(doi: 10.1101/2020.01.20.912733)
Hemidesmosomes modulate force generation via focal adhesions.
W Wang, A Zuidema, L Te Molder, L Nahidiazar, L Hoekman, T Schmidt, S Coppola, A Sonnenberg
The Journal of cell biology
(2020)
219
(doi: 10.1083/jcb.201904137)
Modular actin nano-architecture enables podosome protrusion and mechanosensing
K van den Dries, L Nahidiazar, JA Slotman, MBM Meddens, E Pandzic, B Joosten, M Ansems, J Schouwstra, A Meijer, R Steen, M Wijers, J Fransen, AB Houtsmuller, PW Wiseman, K Jalink, A Cambi
Nature Communications
(2019)
10
(doi: 10.1038/s41467-019-13123-3)
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