TheLeeLab

Publications

Tips on using this search form

  • All search terms are case-insensitive
  • If you specify more than one search option (e.g. you search for both "Authors" and "Paper title") then the publications returned will be those that match all of your search terms
  • To reset the search form, click here
  • Currently displaying 81 - 100 of 252 publications
Author(s)
Publication title
Journal Name
Publication year
Single-molecule fluorescence detection of a tricyclic nucleoside analogue
GN Samaan, MK Wyllie, JM Cizmic, L-M Needham, D Nobis, K Ngo, S Andersen, SW Magennis, SF Lee, BW Purse
Chem Sci
(2020)
12
(doi: 10.1039/d0sc03903a)
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, while the Alzheimer’s R47H mutant does the opposite
A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, M Puigdellívol, A Bruzas, MA Burguillos, RB Dodd, F Chen, Y Zhang, P Flagmeier, L-M Needham, M Enomoto, S Qamar, J Henderson, J Walter, PE Fraser, D Klenerman, SF Lee, P St George-Hyslop, GC Brown
(2020)
(doi: 10.1101/2020.12.03.409995)
Amyloid precipitation in biofluids using a structure-specific chemical antibody
M Rodrigues, P Bhattacharjee, A Brinkmalm, D Do, C Pearson, S De, A Ponjavic, J Varela, F Ruggeri, I Baudrexel, J Lee, A Carr, K Kulenkampff, T Knowles, H Zetterberg, T Snaddon, S Gandhi, S Lee, D Klenerman
(2020)
(doi: 10.21203/rs.3.rs-81521/v1)
vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy
S Lee, A Handa, L-M Needham, A Carr, A Ponjavic, J McColl
Nature Methods
(2020)
17
(doi: 10.1038/s41592-020-0962-1)
Single molecule light field microscopy
R Sims, S Abdul Rehman, MO Lenz, SI Benaissa, E Bruggeman, A Clark, EW Sanders, A Ponjavic, L Muresan, SF Lee, K O'Holleran
Biophotonics and Biomedical Microscopy
(2020)
(doi: 10.1117/12.2584562)
A Comparative Photophysical Study of Structural Modifications of Thioflavin T-Inspired Fluorophores
L-M Needham, J Weber, CM Pearson, DT Do, F Gorka, G Lyu, SE Bohndiek, TN Snaddon, SF Lee
J Phys Chem Lett
(2020)
11
(doi: 10.1021/acs.jpclett.0c01549)
Single molecule light field microscopy
RR Sims, S Abdul Rehman, MO Lenz, SI Benaissa, E Bruggeman, A Clark, EW Sanders, A Ponjavic, L Muresan, SF Lee, K O’Holleran
Optica
(2020)
7
(doi: 10.1364/OPTICA.397172)
Single-molecule visualization of DNA G-quadruplex formation in live cells.
M Di Antonio, A Ponjavic, A Radzevičius, RT Ranasinghe, M Catalano, X Zhang, J Shen, L-M Needham, SF Lee, D Klenerman, S Balasubramanian
Nature chemistry
(2020)
12
(doi: 10.1038/s41557-020-0506-4)
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
FA Aprile, P Sormanni, M Podpolny, S Chhangur, L-M Needham, FS Ruggeri, M Perni, R Limbocker, GT Heller, T Sneideris, T Scheidt, B Mannini, J Habchi, SF Lee, PC Salinas, TPJ Knowles, CM Dobson, M Vendruscolo
Proc Natl Acad Sci U S A
(2020)
117
(doi: 10.1073/pnas.1919464117)
Data analysis in transient electronic spectroscopy – an experimentalist's view
JS Beckwith, CA Rumble, E Vauthey
International Reviews in Physical Chemistry
(2020)
39
(doi: 10.1080/0144235X.2020.1757942)
Distinct domain requirements for EAP45 in HIV budding, late endosomal recruitment, and cytokinesis
B Meng, PPV Ramirez, KM Scherer, E Bruggeman, JC Kenyon, CF Kaminski, AM Lever
bioRxiv
(2020)
(doi: 10.1101/2020.05.23.112607)
Single Molecule Light Field Microscopy
RR Sims, SA Rehman, MO Lenz, A Clark, EW Sanders, A Ponjavic, L Muresan, SF Lee, K O’Holleran
(2020)
(doi: 10.1101/2020.05.20.104802)
ThX - a next-generation probe for the early detection of amyloid aggregates.
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee
Chemical Science
(2020)
11
(doi: 10.1039/c9sc04730a)
Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics
S Basu, O Shukron, D Hall, P Parutto, A Ponjavic, D Shah, W Boucher, D Lando, W Zhang, N Reynolds, L Sober, A Jartseva, R Ragheb, X Ma, J Cramard, R Floyd, G Brown, J Balmer, T Drury, A Carr, L-M Needham, A Aubert, G Communie, K Gor, M Steindel, L Morey, E Blanco, T Bartke, L Di Croce, I Berger, C Schaffitzel, S Lee, T Stevens, D Klenerman, B Hendrich, D Holcman, E Laue
BioRxiv
(2020)
(doi: 10.1101/2020.04.03.003178)
The costs of close contacts: Visualizing the energy landscape of cell contacts at the nanoscale
K Kulenkampff, AH Lippert, J McColl, AM Santos, A Ponjavic, E Jenkins, J Humphrey, A Winkel, K Franze, SF Lee, SJ Davis, D Klenerman
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2020.01.019)
vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy
A Spark, A Kitching, D Esteban-Ferrer, A Handa, AR Carr, L-M Needham, A Ponjavic, M Da Cunha Santos, J McColl, C Leterrier, SJ Davis, R Henriques, SF Lee
(2020)
(doi: 10.1101/2020.01.20.912733)
Hemidesmosomes modulate force generation via focal adhesions
W Wang, A Zuidema, L Te Molder, L Nahidiazar, L Hoekman, T Schmidt, S Coppola, A Sonnenberg
The Journal of cell biology
(2020)
219
(doi: 10.1083/jcb.201904137)
Modular actin nano-architecture enables podosome protrusion and mechanosensing
K van den Dries, L Nahidiazar, JA Slotman, MBM Meddens, E Pandzic, B Joosten, M Ansems, J Schouwstra, A Meijer, R Steen, M Wijers, J Fransen, AB Houtsmuller, PW Wiseman, K Jalink, A Cambi
Nat Commun
(2019)
10
(doi: 10.1038/s41467-019-13123-3)
ThX: a next generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, D T., CK Xu, B Keenlyside, R Cliffe, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee
BIOPHYSICAL JOURNAL
(2019)
121
(doi: 10.1101/713594)
A cell-topography based mechanism for ligand discrimination by the T-cell receptor
RA Fernandes, KA Ganzinger, JC Tzou, P Jönsson, SF Lee, M Palayret, AM Santos, AR Carr, A Ponjavic, VT Chang, C Macleod, BC Lagerholm, AE Lindsay, O Dushek, A Tilevik, SJ Davis, D Klenerman
Proc Natl Acad Sci U S A
(2019)
116
(doi: 10.1073/pnas.1817255116)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
Contacts
Directions

Privacy and cookie policy

About the Department

Departmental Services

Study at Cambridge

About the University

Research at Cambridge