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  • Currently displaying 81 - 100 of 232 publications
Author(s)
Publication title
Journal Name
Publication year
ThX: a next generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee
BIOPHYSICAL JOURNAL
(2019)
121
(doi: 10.1101/713594)
A cell-topography based mechanism for ligand discrimination by the T-cell receptor
RA Fernandes, KA Ganzinger, JC Tzou, P Jönsson, SF Lee, M Palayret, AM Santos, AR Carr, A Ponjavic, VT Chang, C Macleod, BC Lagerholm, AE Lindsay, O Dushek, A Tilevik, SJ Davis, D Klenerman
Proceedings of the National Academy of Sciences
(2019)
116
(doi: 10.1073/pnas.1817255116)
Ion-Pair Dynamics upon Photoinduced Electron Transfer Monitored by Pump-Pump-Probe Spectroscopy.
JS Beckwith, B Lang, J Grilj, E Vauthey
J Phys Chem Lett
(2019)
10
(doi: 10.1021/acs.jpclett.9b01431)
Poly(ADP ribose) links the DNA damage response and biomineralization
K Mueller
Cell Reports
(2019)
27
(doi: 10.1016/j.celrep.2019.05.038)
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms.
S De, DC Wirthensohn, P Flagmeier, C Hughes, FA Aprile, FS Ruggeri, DR Whiten, D Emin, Z Xia, JA Varela, P Sormanni, F Kundel, TPJ Knowles, CM Dobson, C Bryant, M Vendruscolo, D Klenerman
Nature communications
(2019)
10
(doi: 10.1038/s41467-019-09477-3)
Modular actin nano-architecture enables podosome protrusion and mechanosensing
K van den Dries, L Nahidiazar, JA Slotman, MBM Meddens, E Pandzic, B Joosten, M Ansems, J Schouwstra, A Meijer, R Steen, M Wijers, J Fransen, AB Houtsmuller, PW Wiseman, K Jalink, A cambi
(2019)
(doi: 10.1101/583492)
Spectrally-Resolved Photodynamics Of Individual Emitters In Large-Area Monolayers Of Hexagonal-Boron Nitride.
HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee
ACS nano
(2019)
13
(doi: 10.1021/acsnano.9b00274)
Spectrally-Resolved Photodynamics of Individual Emitters in Large-Area Monolayers of Hexagonal-Boron Nitride
HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee
(2019)
(doi: 10.48550/arxiv.1901.02793)
Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale.
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
Nano Letters
(2018)
18
(doi: 10.1021/acs.nanolett.8b02916)
Machine Learning for Analysis of Time-Resolved Luminescence Data
N Dordević, JS Beckwith, M Yarema, O Yarema, A Rosspeintner, N Yazdani, J Leuthold, E Vauthey, V Wood
ACS Photonics
(2018)
5
(doi: 10.1021/acsphotonics.8b01047)
Mechanisms of integrin αVβ5 clustering in flat clathrin lattices.
A Zuidema, W Wang, M Kreft, L Te Molder, L Hoekman, OB Bleijerveld, L Nahidiazar, H Janssen, A Sonnenberg
J Cell Sci
(2018)
131
(doi: 10.1242/jcs.221317)
Sensitive light-sheet microscopy in multiwell plates using an AFM cantilever.
A Ponjavic, Y Ye, E Laue, SF Lee, D Klenerman
Biomedical optics express
(2018)
9
(doi: 10.1364/boe.9.005863)
Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA-mDia2 signaling and filopodium formation.
E Argenzio, J Klarenbeek, KM Kedziora, L Nahidiazar, T Isogai, A Perrakis, K Jalink, WH Moolenaar, M Innocenti
The Journal of biological chemistry
(2018)
293
(doi: 10.1074/jbc.RA118.002779)
Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells
DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M-G Spillantini, D Klenerman, MH Horrocks
Chembiochem : a European journal of chemical biology
(2018)
19
(doi: 10.1002/cbic.201800209)
Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution.
D Klenerman
Analytical chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b02226)
Analysis of nanobody paratopes reveals greater diversity than classical antibodies
LS Mitchell, LJ Colwell
Protein engineering, design & selection : PEDS
(2018)
31
(doi: 10.1093/protein/gzy017)
Fabrication of Scaffold-Based 3D Magnetic Nanowires for Domain Wall Applications.
D Sanz-Hernández, RF Hamans, J Osterrieth, J-W Liao, L Skoric, JD Fowlkes, PD Rack, A Lippert, SF Lee, R Lavrijsen, A Fernández-Pacheco
Nanomaterials (Basel, Switzerland)
(2018)
8
(doi: 10.3390/nano8070483)
FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.
S Basu, L-M Needham, D Lando, EJR Taylor, KJ Wohlfahrt, D Shah, W Boucher, YL Tan, LE Bates, O Tkachenko, J Cramard, BC Lagerholm, C Eggeling, B Hendrich, D Klenerman, SF Lee, ED Laue
Nature Communications
(2018)
9
(doi: 10.1038/s41467-018-04486-0)
Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers.
DR Whiten, D Cox, MH Horrocks, CG Taylor, S De, P Flagmeier, L Tosatto, JR Kumita, H Ecroyd, CM Dobson, D Klenerman, MR Wilson
Cell Reports
(2018)
23
(doi: 10.1016/j.celrep.2018.05.074)
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease
MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, AY Baev, AV Berezhnov, Z Yao, D Little, B Banushi, AS Al-Menhali, RT Ranasinghe, DR Whiten, R Yapom, KS Dolt, MJ Devine, P Gissen, T Kunath, M Jaganjac, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
Nature Communications
(2018)
9
(doi: 10.1038/s41467-018-04422-2)
Yusuf Hamied Department of Chemistry
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