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  • Currently displaying 21 - 40 of 273 publications
Author(s)
Publication title
Journal Name
Publication year
Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson’s disease
JR Evans, M Grant-Peters, JS Beckwith, CE Toomey, R Popovic, JC Breiter, JW Brenton, A Fairbrother-Browne, S Strohbuecker, J Lachica, M Rodriguez-Lopez, EE Brock, B Fu, L Nahidiazar, P Lopez-Garcia, R Ferguson, RS Saleeb, H Lucas-Clarke, A Penverne, K D’Sa, CW Pang, MH Horrocks, M Vendruscolo, N Wood, SF Lee, M Ryten, S Gandhi
(2025)
(doi: 10.1101/2025.08.25.671921)
α-Synuclein driven cell susceptibility in Parkinson’s disease
JC Breiter, JS Beckwith, EE Brock, J Lachica, CE Toomey, B Fu, M Ryten, LE Weiss, NW Wood, S Gandhi, M Vendruscolo, SF Lee
(2025)
(doi: 10.1101/2025.08.19.670819)
DHPSFU: a Fiji plugin for fast and accurate double helix-PSF 3D single-molecule localisation microscopy.
Z Zhang, A Ochirova, S Liu, AD Herbert, Y Wu, W Boucher, SF Lee, ED Laue, D Klenerman, A Ponjavic
Scientific Reports
(2025)
15
(doi: 10.1038/s41598-025-15623-3)
Advanced Imaging and Quantitative Analysis of Alpha Synuclein Aggregates in Parkinson’s Disease Human Brain Tissue
R Tian
(2025)
(doi: 10.17863/CAM.131162)
Patch deconvolution for Fourier light-field microscopy
B Fu, CL Jones, D Heraghty, S Yang, C O’Brien-Ball, V Junghans, H Yang, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee
(2025)
(doi: 10.1101/2025.06.13.659385)
Volumetric single-molecule tracking inside subcellular structures
S Daly, JE Chambers, C Jones, B Fu, JD Manton, JS Beckwith, SJ Marciniak, DC Gershlick, SF Lee
(2025)
(doi: 10.1101/2025.06.09.658280)
Advanced image processing methods for 3D high-throughput microscopy
B Fu
(2025)
(doi: 10.17863/CAM.118852)
The Origin of Single-Molecule Sensitivity in Label-Free Solution-Phase Optical Microcavity Detection
CA Saavedra Salazar, D Sole-Barber, S Wan, JK Rasch, M Reitz, B Cullinane, N Asgari, L-M Needham, J Yuen-Zhou, RH Goldsmith
ACS Nano
(2025)
19
(doi: 10.1021/acsnano.4c16276)
3D super-resolution imaging of PSD95 reveals an abundance of diffuse protein supercomplexes in the mouse brain
S Daly, E Bulovaite, A Handa, K Morris, L Muresan, C Adams, T Kaizuka, A Kitching, A Spark, G Chant, K O Holleran, SGN Grant, MH Horrocks, SF Lee
ACS chemical neuroscience
(2024)
16
(doi: 10.1021/acschemneuro.4c00684)
Vortex light field microscopy: 3D spectral single-molecule imaging with a twist
B Zhang, S Daly, C Zhu, MO Lenz, LE Weiss, L-M Needham, R Peters, SF Lee, K O’Holleran
Optica
(2024)
11
(doi: 10.1364/optica.534148)
Nanoscale T-cell membrane protein imaging across complex topography using accelerated large depth-of-field localisation microscopy
A Ponjavic, A Carr, E Sanders, M Santos, E Jenkins, J McColl, D Klenerman, S Davis, S Lee
BIO Web of Conferences
(2024)
129
(doi: 10.1051/bioconf/202412915001)
3D super-resolution imaging of PSD95 reveals an abundance of diffuse protein supercomplexes in the mouse brain
S Daly, E Bulovaite, A Handa, K Morris, L Muresan, C Adams, T Kaizuka, A Kitching, A Spark, G Chant, K O’Holleran, SGN Grant, MH Horrocks, SF Lee
(2024)
(doi: 10.1101/2024.10.14.617231)
POLCAM: instant molecular orientation microscopy for the life sciences
E Bruggeman, O Zhang, L-M Needham, M Körbel, S Daly, M Cheetham, R Peters, T Wu, AS Klymchenko, SJ Davis, EK Paluch, D Klenerman, MD Lew, K O'Holleran, SF Lee
Nature Methods
(2024)
21
(doi: 10.1038/s41592-024-02382-8)
Evolution of a large periplasmic disk in Campylobacterota flagella enables both efficient motility and autoagglutination
EJ Cohen, T Drobnič, DA Ribardo, A Yoshioka, T Umrekar, X Guo, J-J Fernandez, EE Brock, L Wilson, D Nakane, DR Hendrixson, M Beeby
Dev Cell
(2024)
59
(doi: 10.1016/j.devcel.2024.09.008)
Single-Molecule Sensitivity in Hot Microcavities in the Unstable Regime
CA Saavedra Salazar, D Sole-Barber, N Asgari, B Cullinane, L-M Needham, J Rasch, M Reitz, S Wan, J Yuen-Zhou, R Goldsmith
(2024)
(doi: 10.26434/chemrxiv-2024-xgtxg)
Single-molecule digital sizing of proteins in solution.
G Krainer, RPB Jacquat, MM Schneider, TJ Welsh, J Fan, QAE Peter, EA Andrzejewska, G Šneiderienė, MA Czekalska, H Ausserwoeger, L Chai, WE Arter, KL Saar, TW Herling, TM Franzmann, V Kosmoliaptsis, S Alberti, FU Hartl, SF Lee, TPJ Knowles
Nature Communications
(2024)
15
(doi: 10.1038/s41467-024-50825-9)
Nano-org, a functional resource for single-molecule localisation microscopy data
S Shirgill, DJ Nieves, JA Pike, MA Ahmed, MHH Baragilly, K Savoye, J Worboys, KS Hazime, A Garcia, DJ Williamson, P Rubin-Delanchy, R Peters, DM Davis, R Henriques, SF Lee, DM Owen
(2024)
(doi: 10.1101/2024.08.06.606779)
Vortex light field microscopy: 3D spectral single-molecule imaging with a twist
B Zhang, S Daly, C Zhu, MO Lenz, LE Weiss, L-M Needham, R Peters, SF Lee, K O’Holleran
(2024)
(doi: 10.1101/2024.07.18.604091)
Advances in volumetric super-resolution microscopy and single-particle tracking
S Daly
(2024)
(doi: 10.17863/CAM.113698)
Optimizing performance characteristics of antibodies for single-molecule quantitative bioimaging
JC Breiter, C Loiseau, JS Beckwith, R Andrews, B Fu, PJ Magill, SF Lee, M Vendruscolo
FEBS OPEN BIO
(2024)
14
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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